Novosibirsk researchers explain a DNA-repair enzyme’s flexibility
Crystal structures reveal how endonuclease VIII accommodates different bases.
Paper — 24 September; institute report — 20 October 2026 · 1 min read
Published 22 October 2026 · Source dated 20 October 2026

The ICBFM team, with colleagues from NSU and MIPT, studied bacterial enzyme–DNA complexes. Data were collected at a synchrotron in Shanghai.
Cytosine and thymine opposite the lesion rotate by 180 degrees, helping the enzyme accommodate different bases. The DNA Repair paper explains a molecular mechanism; it does not introduce a new treatment.
Sources & context
- Institute press office — Science in Siberia, 20 October
- DNA Repair — original paper
- Europe PMC — abstract and publication date
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