Molecules · St Petersburg
St Petersburg researchers develop a framework for tuning DNA switches
The model helps set the acidity at which a molecule changes structure.
russia.direct editorial team
Paper: August; RSF report: 23 October 2026 · 1 min read
Published 24 October 2026 · Source dated 23 October 2026
Paper: August; RSF report: 23 October 2026 · 1 min read
Published 24 October 2026 · Source dated 23 October 2026
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St Petersburg University researchers developed design principles for DNA switches that respond to acidity. They tested the approach with 19 designs whose switching thresholds ranged from pH 5.2 to 7.4.
The study examines interactions between two DNA structures, G-quadruplexes and i-motifs, and provides ways to predict their properties. It is a research tool; medical uses remain prospective. The paper appeared in Analytical Chemistry in August, followed by an RSF report on 23 October.
Sources & context
- RSF — report of 23 October
- Research paper — Analytical Chemistry
- Abstract and bibliographic record — Europe PMC
A russia.direct editorial selection based on open sources. Checked 24 October 2026. Practical suggestions are a decision guide, not a promise of outcomes.
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